Medicinal chemistry of anticancer drugs, second edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Anticancer drug discovery from serendipity to rational design. Authoritative and uptodate, handbook of anticancer pharmacokinetics and pharmacodynamics, 2nd edition provides in one comprehensive and highly practical volume a detailed stepbystep guide to the successful design and approval of anticancer drugs. Teicher is the author of anticancer drug development guide 5.
Authoritative and uptodate, anticancer drug development guide. S9 nonclinical evaluation for anticancer pharmaceuticals march 2010. Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Principles of cancer treatment and anticancer drug development. This book explains the mechanisms of anticancer drug resistance and strategies to overcome it. Relevance of tumor models for anticancer drug development. This book consists of 33 chapters in eight independent parts covering various details of drug discovery and development through regulatory. Principles of anticancer drug development cancer drug discovery and development 2011th edition by elizabeth garrettmayer editor, manuel hidalgo editor. Medicinal chemistry of anticancer drugs sciencedirect. The process of anticancer drug discovery leading from natural products to. Teicher, 9781461581543, available at book depository with free delivery worldwide.
These two volumes in the cancer drug discovery and development series reveal how. Preclinical screening, clinical trials, and approval takes oncologists, pharmacologists, medicinal chemists, and other cancer researchers on an encyclopedic tour of the cancer drug development and approval process, moving from the design and execution of highthroughput screens, to preclinical testing, to safety and toxicity testing under fda requirements, to early clinical trials, and on to final fda approval. The book covers many aspects of modern personalized. Road map to anticancer drug development from discovery to nda submission. Principles of anticancer drug development manuel hidalgo. Principles of anticancer drug development cancer drug discovery and development. Understanding the reasons and suggesting potential solutions requires a careful analysis of the grand challenges of anticancer drug development. Preclinical screening, clinical trials, and approval offers cancer researchers an authoritative survey rich in essential insight into the means and methods of cancer drug discovery and approval. Anticancer drug development guide preclinical screening. Principles of anticancer drug development cancer drug discovery. S9 nonclinical evaluation for anticancer pharmaceuticals fda.196 872 1291 85 1241 1427 1482 945 1509 1178 1077 41 1156 1249 597 451 127 333 1522 44 45 472 567 1236 379 610 289 754 1361 362 902 456